Endometrial Cancer: Risk Factors, Stages and Treatments

7Hormone Therapy, Targeted Therapy, and Immunotherapy

People in advanced stages would turn to hormone therapy to treat endometrial cancer. The method could slow the growth of particular cancer cells that have receptors to estrogen and progesterone. Several common types of hormone therapy include:

  • Progestins
  • Tamoxifen
  • Gonadotropin-Releasing Hormone Agonists
  • Aromatase inhibitors (AIs) such as anastrozole, letrozole, and exemestane

These medications are either given as oral pills or injections. Hormone-expressing intrauterine device (IUD) is a distinctive hormone therapy used by your doctor to treat endometrial cancer. The hormonal IUD is a T-shaped plastic device inserted into your uterus and continues to release a small amount of progestin in your body for some years.

Targeted therapy, as the name suggests, uses some drugs to precisely destroy a certain type of cancer cell by stopping tumors from forming new blood vessels (angiogenesis), or targeting the protein of cancer cells. Immunotherapy is an approach to fight cancer cells by strengthening your body’s immune system. Some usual immunotherapies to treat endometrial cancer are immune checkpoint inhibitors, T-cell transfer therapy, monoclonal antibodies, immune system modulators, and treatment vaccines. [6]

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