6Inflammatory Bowel Disease and Genetics
Inflammatory bowel disease is a general term referring to conditions that cause chronic inflammation in the digestive tract. Two common disorders include:
– Crohn’s disease: This condition causes the lining and even deeper layers of the digestive tract to become inflamed
– Ulcerative colitis: This disorder is characterized by sores and inflammation along the superficial linings of the rectum and colon
Both conditions may increase the risk of appendicitis. Typical signs include unexpected weight loss, fatigue, abdominal pain, rectal bleeding, and diarrhea. These problems might range from mild to serious, depending on the underlying cause. [8]
Genetics can be a risk factor in developing appendicitis. This means the condition may run in families. A genetic element could predispose an individual to a blockage of the appendiceal lumen. As a result, the risk can be higher in those with parents or siblings suffering from appendicitis. The likelihood is especially high in men. And the condition is also more prevalent in people between 10 and 30 years old. For children, having cystic fibrosis may increase the risk of developing appendicitis as well. [9]
