5Janus Kinase Inhibitors
If biologics or DMARDs are not effective in treating rheumatoid arthritis, your healthcare provider would prescribe Janus kinase or JAK inhibitors. Common options include upadacitinib, tofacitinib, and baricitinib. They work by affecting the activity of the immune system and genes in the body. This helps reduce inflammation and damage to tissues and joints. There are certain side effects of treatment with JAK inhibitors. These include shingles, flu, sore throat, runny or congested nose, upper respiratory infections, or urinary bladder infections. [5]
