10Death
This might sound surprising, but long-term sleep deprivation would lead to death. It often happens in extremely uncommon conditions like fatal familial insomnia. This is a genetic disorder that causes disrupted and fragmented sleep to the degree that the affected people are unable to fall asleep. As a result, exhaustion and associated issues cause death. In addition, all of the health issues related to sleep deprivation mentioned above can also cause the same fatal result in severe cases. [10]
