Causes of Spinal Muscular Atrophy

By
Peter Evans
-

5Variable Genes

In some rare cases, spinal muscular atrophy can be triggered by other related genes: UBE1 and DYNC1H1. An alteration of the DYNC1H1 gene can happen on chromosome 14. The UBE1 gene can be found on the X-chromosome. It is important to know that X-link inheritance seldom affects women because they have 2 X-chromosomes. Nevertheless, if your mother has the UBE1 gene mutation, she would pass it onto a male baby even when she does not have symptoms of spinal muscular atrophy. [5]

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