Amitriptyline to Prevent Migraine: Dose, Costs, Warnings, and More

By
Mary Salazar
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7Possible Drug Interactions

Amitriptyline may interact with other medications and increase the risk of side effects. In particular, this drug would make it more prone to trouble breathing and drowsiness when taken with opioid painkillers, such as morphine, oxycodone, or codeine. You should also avoid taking amitriptyline with monoamine oxidase inhibitors, a form of antidepressants. This combination may lead to high blood pressure, which can be dangerous. To ensure safety and reduce the risk of interactions, talk with your pharmacist or doctor if you are currently taking or have taken other medications, supplements, vitamins, or herbal remedies. [9]

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