Spinal muscular atrophy is a progressive neurodegenerative condition. This rare genetic disease is often triggered by mutations or alterations in the genes that produce proteins required for motor neuron function. There are many forms of spinal muscular atrophy, which vary in the underlying causes and symptoms. Below are some common causes of spinal muscular atrophy that you should know to reduce the risk and improve the quality of life.
1Common Causes of Spinal Muscular Atrophy
In healthy people, muscles can move when they receive signals from motor neurons located in the spinal cord. Spinal muscular atrophy occurs when these neurons are damaged, making it impossible to transmit signals from the brain to muscles. The condition mostly affects the central nervous system, especially regions associated with movements, such as skeletal muscles, anterior horn in the spinal cord, and motor neurons. The exact cause of spine degeneration over time is a deficiency of survival motor neuron or SMN protein. Without this substance, even existing motor neurons would lose their function and structure. [1]
